- Bajpai J, Translation and Validation of EORTC QLQ-OV28 module into Indian languages (Hindi and Marathi) to study Quality of Life of Ca ovary patients from a tertiary care cancer centre, with manuscript number. South Asian Journal of Cancer.
- Bajpai J, Panda PK, Kagwade S, et al. Translation and validation of European Organization for Research and Treatment for Cancer quality of life questionnaireOV-28 module into Indian languages (Hindi and Marathi) to study quality of life of ovarian cancer patients from a tertiary care cancer center. South Asian J Cancer 2018; 7:37-41
- A Double Blind Randomized Controlled Trial of Renal Protective Effects of Normal Saline Plus Placebo Versus Normal Saline Plus Mannitol Prior to Cisplatin Containing Chemotherapy Regimens in Osteosarcoma and other Solid Tumors (CiNeMa) (ongoing)
- Acupuncture as a modality of treatment for Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer-A Phase 3 Randomized Controlled Trial (ABC-CIPN) (ongoing)
- Early Breast cancer
- Metastatic breast cancer
- Exercise lymphedema
- Breast reconstruction
- Coping with hair loss
- Cervical cancer
- Immuno therapy
Contributing towards many major international and national trials at Tata Memorial Cancer Center.
Trial Details:
| Sr. No. | PI / Co-PI / Co-investigator | Project Title |
|---|---|---|
| Bone and Soft Tissue: | ||
| 1 | PI | Evaluation of VEGF expression of tumor cells as a potential prognostic marker in Ewing’s sarcoma. |
| 2 | PI | A Double Blind Randomized Controlled Trial of Renal Protective Effects of Normal Saline Plus Placebo Versus Normal Saline Plus Mannitol Prior to Cisplatin Containing Chemotherapy Regimens in Osteosarcoma and other Solid Tumors. |
| 3 | PI | A randomized, open label phase III trial evaluating low-dose vs standard-dose Olanzapine with standard triple antiemetic therapy for prevention of highly emetogenic chemotherapy-induced nausea and vomiting in subjects with osteosarcoma and other solid tumors (OLANzaPINE). |
| 4 | PI | MK3475-593-03: A Prospective, Open-label, Phase 4 Study to Evaluate the Safety of Pembrolizumab (KEYTRUDA®) in Subjects with Unresectable or Metastatic Melanoma or PD-L1 positive Non-Small Cell Lung Cancer (NSCLC) in India (Keynote-593). |
| 5 | PI | Randomized, Open-label, Phase III trial of Adjuvant Chemotherapy Versus Observation in Non-metastatic, High risk, Soft Tissue Sarcomas (ACO-Sarc trial). |
| 6 | PI | Translation of EORTC QLQ-BM22 module into Indian language (Marathi) and validation of translated version to study Quality of Life of osteosarcoma patients from tertiary care cancer centre. |
| 7 | Co-PI | TISK Study, a multicentric, observational study (International Sarcoma Kindred Study) to establish a database consisting of bio-specimens, pedigree and epidemiological data to be used as a clinical and research resource and to develop clinically useful, population-based criteria for stratifying hereditary and environmental risk for adult onset sarcoma. |
| Breast: | ||
| 8 | PI | Pregnancy Associated Breast Cancer (PABC) Registry to collate data on epidemiology and treatment patterns & outcomes of PABC. |
| 9 | PI | Randomized multi-centric trial of Oral Metronomic Maintenance Therapy (OMMT) vs Capecitabine (Cape) maintenance in newly diagnosed, locally advanced and/or node positive, non-metastatic triple negative breast cancer (TNBC) patients after completion of standard therapy along with an exploratory study to assess if circulating tumor DNA (ctDNA) and/or circulating tumor cells (CTCs) can be used as a biomarker to predict the probability of recurrence. |
| 9 | PI | Scalp Cooling for the prevention of chemotherapy induced alopecia in breast cancer from a tertiary care cancer center in India. |
| 10 | PI | A Phase III Randomised, Double-Blind, Parallel Group, Multicentre Study to Compare the Efficacy, Safety, Pharmacokinetics and Immunogenicity between SB3 (proposed trastuzumab biosimilar) and Herceptin® in Women with Newly Diagnosed HER2 Positive Early or Locally Advanced Breast Cancer in Neoadjuvant Setting. |
| 11 | PI | A Phase III randomized, double-blind, placebo-controlled study of LEE011 or placebo in combination with Tamoxifen and goserelin or a non-steroidal aromatase inhibitor (NSAI) and goserelin for the treatment of premenopausal women with hormone receptor positive, HER2-negative, advanced breast cancer. |
| 12 | PI | A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Compare NSAI (Anastrozole or Letrozole) plus Abemaciclib, a CDK4 and CDK6 Inhibitor, or plus Placebo, and to Compare Fulvestrant plus Abemaciclib or plus Placebo in Postmenopausal Women with Hormone Receptor-Positive, HER2-Negative Locoregionally Recurrent or Metastatic Breast Cancer. |
| 13 | PI | Prospective study of compliance to maintenance oral hormonal therapy in breast cancer patients from a tertiary care centre. |
| 14 | PI | Retrospective study of demographics, pattern of care and outcome of Young breast cancer patients from a tertiary care cancer centre in India. |
| 15 | PI | Retrospective study of demographics, pattern of care and outcome of TNBC patients from a tertiary care cancer centre in India. |
| Gynecology: | ||
| 16 | PI | Translation of EORTC QLQ-OV28 module into Indian languages (Hindi and Marathi) and validation of translated versions to study Quality of Life of Ca ovary patients from a tertiary care cancer centre. (Part 1) |
| 17 | PI | Study of quality of life of ca ovary patients from a tertiary care cancer centre. (Part 2) |