Extra Mural Matters

Innovative technology to Institute and Country:

Quality of Life issues with cancer care: In cancer and especially in young patients with cancer QOL issues are extremely important and challenging. At times body image issues become so much important that patient deny treatment. Chemotherapy induced alopecia is one of that kind of dreaded side effect.

I have pioneered in our institute and country the first randomised trial to show efficacy of scalp cooling for Chemotherapy Induced alopecia prevention. The results were internationally comparable and published in a high impact journal as follows.

• Bajpai J et al. "Randomised controlled trial of scalp cooling for the prevention of chemotherapy induced alopecia". Breast. 2019 Dec 12; 49:187-193. doi: 10.1016/j.breast.2019.12.004

Output: The results of this trial were practice changing in our country and after this randomised trial it has established the practice in India and Institute with scalp cooling along with chemotherapy (notably we have generated code for revenues generation in Institute as well).

Multidisciplinary, cross country rare tumor boards (ESMO-MSKCC-ISMPO)

I am working towards collaborating with world leaders and institutions to conduct MDT in rare tumours and to provide guidelines in this niche area. This is an unmet need and will benefit patients and care givers hugely. There are few publications in rare tumours (apart from those above mentioned in sarcoma and PABC section).

• Bajpai J, Kapoor A, Jalali R,Gounder M. BMJ Case Rep 2021;14: e240296. doi:10.1136/bcr-2020- 240296
• Sharda M, Bajpai J et.al.(corresponding author). Widely Disseminated Metastatic Ewing sarcoma: Sustained, Complete Metabolic Response to First-Line Oral Metronomic Chemotherapy.PBC-20-0460
• Bajpai J, Chougule A, Chandrani P. Rare mutations in breast cancer and implications in the clinic: Oscillation between sharp horns of dilemmas! Cancer Res Stat Treat 2020; 3: 3026. https://www.crstonline.com/text.asp?2020/3/2/302/287206
• Khanna N, Pandey A, Bajpai J (corresponding author). Metastatic Ewing's Sarcoma: Revisiting the "Evidence on the Fence", with manuscript number Indian J Med Paediatr Oncol. 2017 Apr-Jun; 38(2): 173–181.doi:  4103/ijmpo.ijmpo_24_17
• Bajpai J et.al: A case report of Osteogenicsarcoma with Leprosy Journal of Cancer Research and Therapeutics. 2013; 9:311-3
• Bajpai J et.al. Bilateral adenomyoepithelioma of breast – A case report Journal of Cancer Research and Theraputics2013; 9:523-5.
• Bajpai J, Chauhan B, et al."Billiary Obstruction in a Metastatic Tumor of the Pancreas from Breast Cancer: a Case Report" South Asian J Cancer. 2017 Jan-Mar; 6(1):10. doi: 10.4103/2278-330X.202567.

Collaborative Diagnostic and Translational Research

Collaborative work with the department of pathology is being done to improve care and research in niche areas.

• Rekhi B, Deodhar K, Gulia S, Bajpai J.Raspberry bodies and hyaline globules with positive napsin A immunoexpression are useful features in diagnosing clear cell carcinoma of the female genital tract in cytology samples.2018;29:600–602.
• Rekhi B, Shetty O, Ramadwar M, Rangarajan V, Bajpai J. Role of fine needle aspiration cytology in the diagnosis of a rare case of a poorly differentiated synovial sarcoma with "Rhabdoid" features, including treatment implications. 2017 Jul;45(7):662-667. doi: 10.1002/dc.23712. Epub 2017 Mar 27.
• Rekhi B, Verma V, Gulia A... Bajpai J, Clinicopathological features of a Series of 27 Cases of post-Denosumab treated giant cell tumors of bones: A Single Institutional experience at a Tertiary Cancer Referral Centre, India. Pathol Oncol Res doi:10.1007/s12253-016-0123-0
• Rekhi B, Joshi S, Panchwagh Y... Bajpai J. Clinicopathological features of five unusual cases of intraosseous myoepithelial carcinomas, mimicking conventional primary bone tumours, including EWSR1 rearrangement in one case. APMIS 2016 Apr; 124(4):278-90. 
• Rekhi B, Ramavdhar M, Bajpai J Extraskeletal Myxoid Chondrosarcomas Are Not Characterized by Loss of INI1/SMARCB1: Immuno histochemical Analysis of 16 Cases. J Carcinogen Mutagen 8:280. 2017.Doi:10.4172/2157-2518.1000280

COVID related measures

The pandemic has shaken us and similar time taught us various lessons.I wish to plan  a strategy at the departmental, institutional and national level to be better prepared to handle any such pandemic s in near or far future .I am working in   this area and  contributed towards COVID related care in department and formulating guidelines for treating cancer with COVID in India some of the relevant publications are noted down. I worked with international societies as well and  European Society of Medical Oncology (ESMO) chose me as their Spokesperson to discuss about  COVID and cancer care in an  interview to BBC news channel .

• Ramaswamy A, Nayak L, Moulik NR…Bajpai J et al. COVID-19 in cancer patients on active systemic therapy – Outcomes from LMIC scenario with an emphasis on need for active treatment. Volume9, Issue23, December 2020, Pages 8747-8753; 31 October 2020; https://doi.org/10.1002/cam4.3423
• Tsang J, Bajpai J (corresponding Author)Novel corona virus infection – Knowns and unknowns with particular reference to oncology – Combating against COVID-19 with “COVID.” Indian J Med Paediatric Oncology 0:0, 2020
• Pathak R, Bajpai J (Corresponding author). Tale of Constant Adaptation, Revision, and Change of Cancer Therapy during the Ongoing COVID Crisis: Adapting to Cope and Win. Indian Journal of Medical and Paediatric Oncology | Volume 41 | Issue 2 | March-April 2020
• Jain R, Bajpai J (Corresponding author) IJMPO_198_20, Midst of COVID 19 Crisis – Lookout for One Another to Practice Humanity!  Indian Journal of Medical and Paediatric Oncology, Volume 41, Issue 3, May-June 2020

Bothra M, Shera TA, Bajpai J, Mahajan A. COVID-19: A review of the pandemic with emphasis on the role of imaging. Indian J Med Paediatric Oncology 2020; 41:640-51.